Floatral information
Flotral 10mg Tab 10s Price :107.00
Uses of Flotral 10mg Tab 10s:
Alfuzosin Is In A Group Of Drugs Called Alpha-Adrenergic Blockers. Alfuzosin Relaxes The Muscles In The Prostate And Bladder Neck, Making It Easier To Urinate. Alfuzosin Is Used To Improve Urination In Men With Benign Prostatic Hyperplasia (Enlarged Prostate). Alfuzosin May Also Be Used For Other Purposes Not Listed In This Medication Guide.
Side Effects of Flotral 10mg Tab 10s:
Drowsiness, Postural Hypotension, Syncope, Asthenia, Depression, Headache, Dry Mouth, GI Disturbances, Edema, Blurred Vision, Rhinitis, Erectile Disorders, Tachycardia, Palpitation, Hypersensitivity Reactions; Flushes; Chest Pain; Dizziness; Lack Of Energy.
Drug Interactions of Flotral 10mg Tab 10s:
CYP3A4 Inhibitors E.g. Azole Antifungals, Clarithromycin, Diclofenac, Doxycycline, Erythromycin, Imatinib, Isoniazid, Nefazodone, Nicardipine, Propofol, Protease Inhibitors, Quinidine, Telithromycin, And Verapamil May Increase The Levels Of Alfuzosin. Reduced Serum Levels When Used With CYP3A4 Inducers E.g. Aminoglutethimide, Carbamazepine, Nafcillin, Nevirapine, Phenobarbital, Phenytoin And Rifamycins. Potentially Fatal: Concurrent Use With Potent CYP3A4 Inhibitors (E.g. Itraconazole, Ketoconazole Or Ritonavir) Is Contraindicated.
Contraindications of Flotral 10mg Tab 10s:
Severe Hepatic Impairment; History Of Postural Hypotension And Micturition Syncope; Intestinal Occlusion; Severe Renal Insufficiency; Lactation.
Mechanism of Action of Flotral 10mg Tab 10s:
Alfuzosin Is A Quinazoline-Derivative Which Exhibits Selectivity For Α1-Adrenergic Receptors In The Lower Urinary Tract. Blockade Of These Adrenoreceptors Causes Relaxation Of Smooth Muscle In The Bladder Neck And Prostate, Resulting In Improvement In Urine Flow And A Reduction In Symptoms Of Benign Prostatic Hyperplasia. Absorption: Readily Absorbed After Oral Admin. Bioavaliability: About 64%. Distribution: 90% Bound To Plasma Proteins. Metabolism: Extensively Metabolised In The Liver, Mainly By The Cytochrome P450 Isoenzyme CYP3A4, To Inactive Metabolites. Excretion: About 11% Excreted Unchanged In Urine. Metabolites Are Mainly Excreted In Faeces Via Bile. Elimination Half-Life: About 3-5 Hr.
Special Precautions for Flotral 10mg Tab 10s:
Elderly; Hypertension; Coronary Insufficiency; Angina (Discontinue); Renal Or Hepatic Impairment. Monitor BP Regularly. May Affect Ability To Drive Or Operate Machinery.
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