Can an anal fissure cause blood pressure rise ,urinary infection, prostrate pain ,piles inflammation? Yes I will post test results later after applying ano metrogyl on the fissure.the urine culture showed no growth! Also the anal fissure inflamed the small intestine . If you go to a gasteo he has no idea maybe eating outside food urologist also thinks about antibiotics but sometimes the bacteria gets resistant.so if you have ecoli or kelbsiella in your urine culture or semen culture first fix that hidden anal fissure. And long term anal fissure cause problems with senior citizen electrolytes? Let the scientist do the tests.